Enzymes are proteins. Proteins are long chains of amino acids linked to
each other by peptide bonds. Aminoacids have many functional groups
in their structure. These functional groups are, many of them at least,
ionisable. As they are weak acids and bases in chemical nature, this
ionization is influenced by the pH of the solution. For many enzymes, activity
is influenced by the surrounding pH. This is depicted in the curve below,
explain briefly.

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The dependence of enzyme on pH is due to the presence of charged amino acid at its active site, variation causes changes in charge of amino acid. The enzymatic activity decreases when pH is less than the optimum pH.
