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Practice each question, then open the answer or worked solution.
Name the site (s) of pyruvate synthesis. Also, write the chemical reaction wherein pyruvic acid dehydrogenase acts as a catalyst.
The site of pyruvate synthesis is Cytoplasm in the cell.
Pyruvate dehydrogenase → Pyruvic acid + CoA + NAD+ Acetyl CoA + CO2 + NADH + H+
Mention the important series of events of aerobic respiration that occur in the matrix of the mitochondrion and the inner membrane of the mitochondrion.
i) Citric Acid Cycle/ Tricarboxylic acid cycle: It occurs in the mitochondrial matrix of the cell.
ii) Electron transport system/ Oxidative phosphorylation: It occurs in the inner mitochondrial membrane of the cell.
The respiratory pathway is believed to be a catabolic pathway. However, the nature of the TCA cycle is amphibolic. Explain.
The respiratory pathway is believed to be a catabolic pathway because it breakdown the substrate. In the TCA cycle, the pyruvate is further broken down to Acetyl CoA, and this Acetyl CoA can also be synthesized to fatty acid whenever it is required for fatty acid metabolism or synthesis. In this cycle both breakdown and synthesis take place.