Infectious Diseases and Pathogenicity - Microbial Diseases and Host Pathogen Interaction - Life Sciences Previous Year Questions

1

2007 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2007

Peptic ulcers are caused by

A

Shigella sonei

B

Giardia lambia

C

Enterobius vermicularis

D

Helicobacter pylori

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2

2007 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2007

Which of the following disease is NOT caused by the Coxsackie virus?

A

Intestinal infection

B

Meningitis

C

Gingivitis

D

Myocarditis

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3

2009 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2009

Which one of the following bacterial toxins does NOT have ADP ribosylation activity ?

A

Diphtheria toxin

B

Cholera toxin

C

S. aureus α-toxin

D

Pseudomonas exotoxin

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4

2009 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2009

Cholera toxin acts by

A

Activating a G-protein

B

Blocking an ion channel

C

Activating synaptic transmission

D

Blocking glycolysis

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5

2010 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2010

Match the pathogen in Group I with the corresponding disease in Group II
Group I
P. Bacteria
Q. Virus
R. Fungi
S. Protozoa
Group II
1. Measles
2. Candidiasis
3. Malaria
4. Bovine spongiform encephalitis
5. Tuberculosis

A

P-1, Q-2, R-4, S-5

B

P-1, Q-4, R-2, S-3

C

P-5, Q-1, R-4, S-2

D

P-5, Q-1, R-2, S-3

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6

2011 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2011

Match the name of the disease with the causal organism

A

P-1, Q-5, R-2, S-4

B

P-4, Q-3, R-2, S-1

C

P-6, Q-2, R-4, S-1

D

P-5, Q-3, R-2, S-4

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7

2011 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2011

A newly emerged variant of Influenza virus can be selectively propagated from the mixed population by addition of

A

Gancyclovir

B

Tamiflu

C

Interferon gamma

D

Neutralizing antibody

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8

2011 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2011

Which of the statements about Corynebacterium diphtheriae biology is NOT CORRECT?

A

All strains of C. diphtheriae are producers of diphtheria toxin

B

Diphtheria toxin production can be minimized by high concentration of iron in the medium

C

Diphtheria toxin inhibits protein synthesis

D

Diphtheria toxin is an A-B toxin secreted as a polypeptide of 62 kDa

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9

2011 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2011

Which of the following group of characteristics is CORRECT in respect of Shigella species found as food pathogen?

A

Gram positive, motile by gliding, spore forming cocci and transmitted by contaminated food

B

Gram negative, motile by flagella, spore forming bacilli and transmitted by contaminated water

C

Gram positive, non-motile, non-spore forming cocci and transmitted by contaminated air and water both

D

Gram negative, non-motile, non-spore forming and transmitted by fecal-oral route

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10

2012 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2012

Which one of the following bacterial toxins does NOT have ADP-ribosyl transferase activity?

A

Pertussis toxin

B

Diphtheria toxin

C

Pseudomonas Exotoxin A

D

S. aureus α-toxin

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11

2012 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2012

Which ONE of the following statements about E.coli is NOT true?

A

E.coli was the first disease- causing bacterium identified by Robert Koch

B

E.coli is part of the normal microbiota of humans

C

Certain E.coli strains can cause bloody diarrhoea

D

E.coli is beneficial to human

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12

2012 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2012

Match the disease in Group I with their corresponding organism in Group II
Group I
P. African sleeping sickness
Q. Rocky mountain spotted fever
R. Mumps
S. Filariasis
Group II
I. Rubulavirus
II. Trypanosoma brucei
III. Wuchereria bancrofti
IV. Rickettsia rickettsii
V. Leishmania donovani

A

P-III, Q-V, R-II, S-I

B

P-II, Q-I, R-III, S-IV

C

P-II, Q-IV, R-I, S-III

D

P-I, Q-V, R-II, S-IV

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13

2013 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2013

A patient suffering from pneumonia and tuberculosis was found to have very low CD4+ T cells. In all probability the PRIMARY causative infectious agent belongs to

A

Klebsiella family

B

Mycobacterium family

C

Retrovirus family

D

Streptococcus family

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14

2013 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2013

Match the infectious agents in Group I with the associated diseases in Group II

Group I	Group II
P. Bordetellapertussis	I. Mumps
Q. Mycobacterium leprae	II. Meningitis
R. Haemophilusinfluenzae	III. Tuberculosis
S. Rubella	IV. Whooping cough
	V. Hansen’s disease

A

P-IV, Q-V, R-II, S-I

B

P-V, Q-III, R-I, S-IV

C

P-I, Q-III, R-V, S-IV

D

P-III, Q-II, R-V, S-I

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15

2013 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2013

The food borne disease, Q fever is caused by the organism

A

Clostridium perfringens

B

Coxiella burnetii

C

Bacillus cereus

D

Staphylococcus aureus

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16

2016 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2016

Which of the following infectious agents cross the blood-brain barrier?
(P) Streptococcus pneumoniae (Q) Coxsackie virus
(R) Rotavirus (S) Streptococcus pyogenes

A

P & S

B

R & S

C

P & Q

D

Q & R

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17

2016 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2016

Which ONE of the following is often a life-threatening systemic inflammatory response?

A

Tuberculosis

B

Lupus erythematosus

C

Septic shock

D

Hypertension

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18

2017 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2017

Which one of the following is a contagious disease?

A

Chickenpox

B

Tetanus

C

Malaria

D

Filariasis

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19

2017 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2017

Match the diseases given in Group I with their causative agents from Group II.

Group I
(P) Plague
(Q) Rabies
(R) Q fever
(S) Malaria

Group II
(I) Coxiella burnetii
(II) Plasmodium spp.
(III) Yersinia pestis
(IV) Lyssavirus

A

P-III, Q-IV, R-I, S-II

B

P-III, Q-I, R-II, S-IV

C

P-IV, Q-III, R-I, S-II

D

P-III, Q-I, R-IV, S-II

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20

2018 · Life Sciences · Microbial Diseases and Host Pathogen Interaction · Infectious Diseases and Pathogenicity

Life Sciences (XL) 2018

Match the microorganisms to their predominant modes of transmission.

A

(i)-(r), (ii)-(p), (iii)-(s), (iv)-(q)

B

(i)-(s), (ii)-(q), (iii)-(p), (iv)-(r)

C

(i)-(q), (ii)-(p), (iii)-(s), (iv)-(r)

D

(i)-(s), (ii)-(r), (iii)-(p), (iv)-(q)

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