Cell Structure, Organelles and Microscopy - Cell Biology - Life Sciences Previous Year Questions

1

2007 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2007

Which of the following enzyme activities can be detected in the supernatant obtained by centrifugation of liver homogenate at 100,000 g for 1 hr at 4°C?

A

Succinate dehydrogenase

B

Glyceraldehyde 3-phosphate dehydrogenase

C

Glycogen synthetase

D

Aconitase

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2

2007 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2007

F1F0-ATPase in chloroplasts is located on the

A

inner chloroplast membrane with F1 facing the stroma

B

inner chloroplast membrane with F1 facing the inter-membrane space

C

thylakoid membrane with F1 facing the stroma

D

thylakoid membrane with F1 facing the thylakoid lumen

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3

2007 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2007

Which of the following reagents is used for harvesting anchorage-dependent animal cells from culture vessels?

A

Trypsin/Collagenase

B

Trypsin/Collagen

C

Collagen/Fibronectin

D

DMSO

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4

2007 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2007

Determine the correctness or otherwise of the following Assertion [a] and Reason [r]
Assertion: Enzymatic method of tissue dispersion is milder than chemical and mechanical methods.
Reason: Enzymes work at optimal temperature and pH

A

Both [a] and [r] are true and [r] is the correct reason for [a]

B

Both [a] and [r] are true but [r] is not the correct reason for [a]

C

[a] is true but [r] is false

D

[a] is false but [r] is true

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5

2007 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2007

A microscope that has a total magnification of 1500X with an oil immersion lens has an ocular of power

A

1.5X

B

15X

C

150X

D

1500X

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6

2007 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2007

For cloning an animal, which of the following somatic cells would not be suitable ?

A

Lymphocytes

B

Fibroblasts

C

Epidermal cell

D

Neutrophils

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7

2009 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2009

In a normal animal cell, the extra-chromosomal DNA is

A

Single stranded circular

B

Single stranded linear

C

Double stranded circular

D

Double stranded linear

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8

2010 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2010

Nucleolus is involved in the synthesis of

A

rRNA

B

tRNA

C

DNA

D

mRNA

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9

2012 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2012

The number of nucleosomes present in a 30 nm solenoid structure of a chromatin is

A

2

B

4

C

6

D

8

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10

2014 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2014

A green fluorescent protein (GFP) encoding gene is fused to a gene encoding specific protein for expression in cells. What is the advantage of using GFP over staining cells with fluorescently labeled antibodies that bind to the target protein?

A

It bleaches less compared to fluorescent probes

B

It allows imaging at higher resolution than fluorescent probes.

C

It provides more precise location of the protein than fluorescent probes.

D

Its fusion allows tracking the location of the protein in living cells, while staining usually requires fixation of cells.

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11

2015 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2015

Nuclear membrane is absent in

A

Chlamydomonas

B

Nostoc

C

Volvox

D

Chlorella

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12

2016 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2016

Detoxification of alcohol occurs in liver cells where peroxisomal enzymes remove hydrogen from it, which is

A

combined with water molecules to generate hydrogen peroxide.

B

used to break down hydrogen peroxide.

C

transferred to the mitochondria.

D

transferred to oxygen molecules to generate hydrogen peroxide.

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13

2019 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2019

Which of the following cellular structures are absent in eukaryotes and are present at least in some prokaryotic organisms? (i) Respiratory enzymes (ii) Ribosomes (iii) Nucleoid (iv) Internal membranes (v) Pili

A

(iii) and (v)

B

(i) and (iv)

C

(i), (iii) and (v)

D

(iii), (iv)

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14

2019 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2019

In eukaryotic chromatin organization, which one of the histones seals off the nucleosome at the location at which linker DNA enters and leaves the nucleosome?

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15

2019 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2019

Consider a spherical bacterial cell with diameter 2 μm and a eukaryotic cell of spherical shape with a diameter of 20 μm. The surface area to volume (in μm⁻¹) ratio of the bacterial cell (round off to 1 decimal place) is ____ times more than that of the eukaryotic cell.

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16

2020 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2020

Match the cellular organelle in Group I with its function in Group II

Group I      Group II
P. Golgi apparatus      1. Lipid degradation
Q. Nucleolus      2. Protein degradation
R. Peroxisome      3. Protein sorting
S. Proteasome      4. Ribosomal RNA synthesis

A

P-3, Q-2, R-1, S-4

B

P-3, Q-4, R-1, S-2

C

P-1, Q-2, R-4, S-3

D

P-3, Q-1, R-4, S-2

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17

2021 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2021

Which one of the following cells lack hypoxanthine-guanine phosphoribosyltransferase (HGPRT)?

A

B Cell

B

T Cell

C

Macrophage

D

Myeloma Cell

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18

2022 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2022

Match the cell types listed in Column I with their sources in Column II and the primary functional roles listed in Column III.

Column I	Column II	Column III
P. Microglial cells	(i) Lung	a. Visual transduction
Q. Leydig cells	(ii) Eyes	b. Hormone secretion
R. ON cells	(iii) Brain	c. Phagocytosis
S. Pneumocytes	(iv) Testis	d. Gaseous exchange

A

P-(iii)-b, Q-(iv)-c, R-(ii)-a, S-(i)-d

B

P-(ii)-c, Q-(iv)-d, R-(i)-a, S-(iii)-b

C

P-(i)-a, Q-(iv)-b, R-(ii)-c, S-(iii)-d

D

P-(iii)-c, Q-(iv)-b, R-(ii)-a, S-(i)-d

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19

2023 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2023

DNA in a 1 cm long chromatin contains 5 × 10⁹ base pairs. The fold compaction of this DNA within the chromatin is ______ (in integer).

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20

2025 · Life Sciences · Cell Biology · Cell Structure, Organelles and Microscopy

Life Sciences (XL) 2025

The DNA double helix measures 0.34 nm/bp. The diameter of a nucleosome core particle is 11 nm. If the ratio of wrapped DNA length to nucleosome diameter is 4.51, the length of DNA around the nucleosome (to the nearest integer) is ______ bp.

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