Cell Biology - Genetics, Cellular and Molecular Biology - Biotechnology Previous Year Questions

1

2016 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2016

In a typical mitotic cell division cycle in eukaryotes, M phase occurs immediately after the

A

G₀ phase

B

S phase

C

G₁ phase

D

G₂ phase

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2

2016 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2016

Which one of the following statements regarding G proteins is INCORRECT?

A

GDP is bound to G protein in the resting stage

B

GTP bound α subunit cannot reassemble with βγ dimer

C

All G proteins are trimeric

D

Activation of G protein may result in activation or inhibition of the target enzymes

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3

2017 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2017

Secretory proteins synthesized by ER-associated ribosomes traverse through

A

mitochondria

B

peroxisomes

C

the Golgi apparatus

D

the nucleus

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4

2017 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2017

In eukaryotes, cytokinesis is inhibited by

A

cytochalasin D

B

vinblastine

C

nocodazole

D

colchicine

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5

2017 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2017

Match the proteins in Group I with cellular processes in Group II

Group I	Group II
P. p53	1. DNA packaging
Q. Lysozyme	2. Apoptosis
R. Tubulins	3. Hydrolysis of polysaccharides
S. Histones	4. Chromosome segregation

A

P-4, Q-2, R-3, S-1

B

P-2, Q-3, R-1, S-4

C

P-4, Q-3, R-1, S-2

D

P-2, Q-3, R-4, S-1

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6

2017 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2017

The genome is diploid at the end of which phases of a human mitotic cell cycle?

A

G2 & S

B

G1 & M

C

M & S

D

G1 & G2

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7

2018 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2018

Which one of the following statements is true for actin?

A

Actin filament is structurally polarized and the two ends are not identical

B

De novo actin polymerization is a single-step process

C

The pointed end of the actin filaments is the fast growing end

D

Actin forms spindle fibers during mitosis

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8

2018 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2018

A single stem cell undergoes 10 asymmetric cell divisions. The number of stem cells at the end is __________

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9

2019 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2019

Match the organelles in Group I with their functions in Group II.

A

P-1, Q-3, R-2, S-5

B

P-1, Q-4, R-5, S-3

C

P-2, Q-5, R-3, S-4

D

P-1, Q-3, R-4, S-5

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10

2019 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2019

DNA synthesis in eukaryotes occurs during which phase of the mitotic cell cycle?

A

M

B

G1

C

S

D

G0

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11

2020 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2020

Match sub-cellular organelles listed in Group I with their features listed in Group II:

A

P-1, Q-4, R-2, S-3

B

P-2, Q-3, R-4, S-1

C

P-3, Q-4, R-2, S-1

D

P-3, Q-1, R-4, S-2

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12

2020 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2020

Determine the correctness or otherwise of the following Assertion [a] and the Reason [r].

Assertion [a]: A zygote and its immediate descendant cells are unspecialized and are called totipotent

Reason [r]: Totipotent cells retain the capacity to differentiate into only a few cell types

A

Both [a] and [r] are false

B

Both [a] and [r] are true but [r] is not the correct reason for [a]

C

Both [a] and [r] are true and [r] is the correct reason for [a]

D

[a] is true but [r] is false

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13

2020 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2020

Determine the correctness or otherwise of the following Assertion [a] and the Reason [r] regarding mammalian cells.
Assertion [a]: Cells use Ca²⁺, and not Na⁺, for cell-to-cell signaling
Reason [r]: In the cytosol, concentration of Na⁺ is lower than that of Ca²⁺

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14

2021 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2021

The process by which intracellular macromolecules are supplied for lysosomal degradation during nutrient starvation is

A

apoptosis

B

autophagy

C

phagocytosis

D

pinocytosis

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15

2021 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2021

Which of the following layer(s) is/are formed from the inner cell mass of the blastocyst?

A

Ectoderm

B

Endoderm

C

Mesoderm

D

Trophectoderm

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16

2021 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2021

Which of the following cell organelle(s) is/are surrounded by a single phospholipid membrane?

A

Golgi apparatus

B

Lysosome

C

Mitochondria

D

Nucleus

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17

2022 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2022

Match the component of eukaryotic cells (Column I) with its respective function (Column II).

Column I	Column II
P. Lysosome	1. Digestion of macromolecules
Q. Peroxisome	2. Detoxification of harmful compounds
R. Glyoxysome	3. Conversion of fatty acids to sugar
S. Cytoskeleton	4. Involvement in cell motility

A

P-1, Q-2, R-3, S-4

B

P-2, Q-1, R-3, S-4

C

P-3, Q-1, R-2, S-4

D

P-4, Q-3, R-1, S-2

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18

2022 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2022

The enzymes involved in ubiquitinylation of cell-cycle proteins are

A

E1 and E2 only

B

E1 and E3 only

C

E1 and E4 only

D

E1, E2 and E3

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19

2022 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2022

Which of the following statement(s) regarding trafficking in eukaryotic cells is(are) CORRECT?

A

Dynamin binds GTP and is involved in vesicle budding

B

Dynamin is involved in cytoskeletal remodelling

C

Dynein binds ATP and is involved in movement of organelles along microtubules

D

Dynein binds GTP and is involved in movement of organelles along microtubules

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20

2023 · Biotechnology · Genetics, Cellular and Molecular Biology · Cell Biology

Biotechnology (BT) 2023

Dendritic cells are involved in cross-presentation of antigens. Which of the following protein(s) is(are) required for cross-presentation?
P. Basic leucine zipper ATF-like transcription factor 3 (BATF3)
Q. Membrane associated ring-CH-type finger 1 (MARCH-1)
R. Solute carrier family 10 member 1 (SLC10A1)
S. Class II-associated invariant chain peptide (CLIP)

A

P only

B

P and R only

C

P, Q and R only

D

S only

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