LIFE SCIENCE PART C (DECEMBER 2018) 2018

Following are statements on β-turns:1) All the 20 coded amino acids have equal propensity to form β-turns.2) Pro cannot occur in β-tums.3) Pro-Gly sequence strongly favours β-turns.4) In Asn-Gly β-turns, Asn can have positive Φ, Ψ values.Choose the combination with all correct statements

DNA melting temperature (Tm) was found to be 47°C and enthalpy measured at Tm Was 0.032 kJ. The entropy change would be:

Match the following bonds with their approximate energies:

The following are some statements regarding glycolysis:(A) Glycolysis is not regulated by pyruvate kinase.(B) Lactate can be an end product of glycolysis.(C) Glycolysis cannot function anaerobically.(D) In erythrocytes, the second site in glycolysis for ATP generation can be bypassed.From the above, choose the combination with both INCORRECT statements:

For a reversible non-competitive inhibition of an enzyme, choose the plot that you would use to determine Km:

An investigator expresses a GFP-fused protein that localizes to the outer membrane of the Golgi apparatus. Upon visualizing GFP-signal in the fluorescence microscope, it was noted that GFP is pericentrosomal in its localization (Fig A). Treatment of such GFP expressing cells with a newly identified drug disrupted the Golgi into small vesicles (Fig B).Following is a list of potential targets of the drug:(A) Dynein complex(B) Myosin(C) Microtubules(D) DicerChoose the combination with all correct targets: